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Turetsky, B. I., Bilker, W. B., Siegel, S. J., Kohler, C. G., and Gur, R. E., "Profile of auditory information-processing deficits in schizophrenia" Psychiatry research (2009) 165(1-2): 27.
Ehrlichman, R. S., Gandal, M. J., Maxwell, C. R., Lazarewicz, M. T., Finkel, L. H., Contreras, D., Turetsky, B. I., and Siegel, S. J., "N-methyl-d-aspartic acid receptor antagonist-induced frequency oscillations in mice recreate pattern of electrophysiological deficits in schizophrenia" Neuroscience (2009) 158(2): 705.
Rudnick, N. D., Koehler, C., Picciotto, M. R., and Siegel, S. J., "Role of beta2-containing nicotinic acetylcholine receptors in auditory event-related potentials" Psychopharmacology (2008).
Ragland, J. D., Moelter, S. T., Bhati, M. T., Valdez, J. N., Kohler, C. G., Siegel, S. J., Gur, R. C., and Gur, R. E., "Effect of retrieval effort and switching demand on fMRI activation during semantic word generation in schizophrenia" Schizophrenia research (2008) 99(1-3): 312.
Rabin, C., Liang, Y., Ehrlichman, R. S., Budhian, A., Metzger, K. L., Majewski-Tiedeken, C., Winey, K. I., and Siegel, S. J., "In vitro and in vivo demonstration of risperidone implants in mice" Schizophrenia research (2008) 98(1-3): 66.
Majewski-Tiedeken, C. R., Rabin, C. R., and Siegel, S. J., "Ketamine exposure in adult mice leads to increased cell death in C3H, DBA2 and FVB inbred mouse strains" Drug and alcohol dependence (2008) 92(1-3): 217.
Kelly, M. P., Cheung, Y. F., Favilla, C., Siegel, S. J., Kanes, S. J., Houslay, M. D., and Abel, T., "Constitutive activation of the G-protein subunit Galphas within forebrain neurons causes PKA-dependent alterations in fear conditioning and cortical Arc mRNA expression" Learning & memory (Cold Spring Harbor, N.Y (2008) 15(2): 75.
Halene, T. B. and Siegel, S. J., "Antipsychotic-like properties of phosphodiesterase 4 inhibitors: evaluation of 4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone (RO-20-1724) with auditory event-related potentials and prepulse inhibition of startle" The Journal of pharmacology and experimental therapeutics (2008) 326(1): 230.
Gandal, M. J., Ehrlichman, R. S., Rudnick, N. D., and Siegel, S. J., "A novel electrophysiological model of chemotherapy-induced cognitive impairments in mice" Neuroscience (2008) 157(1): 95.
Ehrlichman, R. S., Maxwell, C. R., Majumdar, S., and Siegel, S. J., "Deviance-elicited changes in event-related potentials are attenuated by ketamine in mice" Journal of cognitive neuroscience (2008) 20(8): 1403.
Dankert, M. E., Brensinger, C. M., Metzger, K. L., Li, C., Koleva, S. G., Mesen, A., Laprade, B., Wiguna, T., Han, C., Farooq, S., Severus, W. E., Gayares, J. G., Langosch, J. M., Lallart, X., Tateno, M., Mihai, A., Nair, S. R., Belmaker, R., Rybakowski, J., Owe-Larsson, B., Kane, J. M., Johnstone, E. C., MacIntyre, D. J., Malhotra, S., Gonzalez-Pinto, A., Mosquera, F., Babb, S. M., Habib pour, E., Fatemi, S. S., Swanson, C., Adler, C., Young, A., Hoeft, F., Sivakumar, K., Radoeva, P. D., Lallart, E. A., Bilker, W. B., and Siegel, S. J., "Attitudes of patients and family members towards implantable psychiatric medication" Schizophrenia research (2008) 105(1-3): 279.
Budhian, A., Siegel, S. J., and Winey, K. I., "Controlling the in vitro release profiles for a system of haloperidol-loaded PLGA nanoparticles" International journal of pharmaceutics (2008) 346(1-2): 151.
Amann, L. C., Phillips, J. M., Halene, T. B., and Siegel, S. J., "Male and female mice differ for baseline and nicotine-induced event related potentials" Behavioral neuroscience (2008) 122(5): 982.
Siegel, S. J., O'Neill, C., Dube, L. M., Kaldeway, P., Morris, R., Jackson, D., and Sebree, T., "A unique iontophoretic patch for optimal transdermal delivery of sumatriptan" Pharmaceutical research (2007) 24(10): 1919.
Siegel, S. J., Bieschke, J., Powers, E. T., and Kelly, J. W., "The oxidative stress metabolite 4-hydroxynonenal promotes Alzheimer protofibril formation" Biochemistry (2007) 46(6): 1503.
Phillips, J. M., Siegel, S. J., Shields, A. E., Patterson, F., Gould, T. J., Strasser, A. A., Ray, R., Pinto, A., Audrain-McGovern, J., Rukstalis, M., Perkins, K. A., Blendy, J. A., and Lerman, C., "Translating basic science to improve pharmacotherapy for nicotine dependence" Nicotine Tob Res (2007) 9 Suppl 4S583.
Phillips, J. M., Ehrlichman, R. S., and Siegel, S. J., "Mecamylamine blocks nicotine-induced enhancement of the P20 auditory event-related potential and evoked gamma" Neuroscience (2007) 144(4): 1314.
Metzger, K. L., Shoemaker, J. M., Kahn, J. B., Maxwell, C. R., Liang, Y., Tokarczyk, J., Kanes, S. J., Hans, M., Lowman, A. M., Dan, N., Winey, K. I., Swerdlow, N. R., and Siegel, S. J., "Pharmacokinetic and behavioral characterization of a long-term antipsychotic delivery system in rodents and rabbits" Psychopharmacology (2007) 190(2): 201.
Metzger, K. L., Maxwell, C. R., Liang, Y., and Siegel, S. J., "Effects of nicotine vary across two auditory evoked potentials in the mouse" Biological psychiatry (2007) 61(1): 23.
Lerman, C., LeSage, M. G., Perkins, K. A., O'Malley, S. S., Siegel, S. J., Benowitz, N. L., and Corrigall, W. A., "Translational research in medication development for nicotine dependence" Nature reviews (2007) 6(9): 746.
Kelly, M. P., Isiegas, C., Cheung, Y. F., Tokarczyk, J., Yang, X., Esposito, M. F., Rapoport, D. A., Fabian, S. A., Siegel, S. J., Wand, G., Houslay, M. D., Kanes, S. J., and Abel, T., "Constitutive activation of Galphas within forebrain neurons causes deficits in sensorimotor gating because of PKA-dependent decreases in cAMP" Neuropsychopharmacology (2007) 32(3): 577.
Kanes, S. J., Tokarczyk, J., Siegel, S. J., Bilker, W., Abel, T., and Kelly, M. P., "Rolipram: a specific phosphodiesterase 4 inhibitor with potential antipsychotic activity" Neuroscience (2007) 144(1): 239.
Hans, M. L., Maxwell, C., Ehrlichman, R. S., Metzger, K., Liang, Y., Siegel, S. J., and Lowman, A. M., "Evaluation of in vitro release and in vivo efficacy of mPEG-PLA-haloperidol conjugate micelle-like structures" Journal of biomedical materials research (2007) 83(2): 422.
Halene, T. B. and Siegel, S. J., "PDE inhibitors in psychiatry--future options for dementia, depression and schizophrenia?" Drug discovery today (2007) 12(19-20): 870.
Gur, R. E., Turetsky, B. I., Loughead, J., Snyder, W., Kohler, C., Elliott, M., Pratiwadi, R., Ragland, J. D., Bilker, W. B., Siegel, S. J., Kanes, S. J., Arnold, S. E., and Gur, R. C., "Visual attention circuitry in schizophrenia investigated with oddball event-related functional magnetic resonance imaging" The American journal of psychiatry (2007) 164(3): 442.
Budhian, A., Siegel, S. J., and Winey, K. I., "Haloperidol-loaded PLGA nanoparticles: systematic study of particle size and drug content" International journal of pharmaceutics (2007) 336(2): 367.
Siegel, S. J., Kahn, J. B., Metzger, K., Winey, K. I., Werner, K., and Dan, N., "Effect of drug type on the degradation rate of PLGA matrices" Eur J Pharm Biopharm (2006) 64(3): 287.
Siegel, S. J., Irani, F., Brensinger, C. M., Kohler, C. G., Bilker, W. B., Ragland, J. D., Kanes, S. J., Gur, R. C., and Gur, R. E., "Prognostic variables at intake and long-term level of function in schizophrenia" The American journal of psychiatry (2006) 163(3): 433.
Roalf, D. R., Turetsky, B. I., Owzar, K., Balderston, C. C., Johnson, S. C., Brensinger, C. M., Gur, R. E., Siegel, S. J., and Moberg, P. J., "Unirhinal olfactory function in schizophrenia patients and first-degree relatives" The Journal of neuropsychiatry and clinical neurosciences (2006) 18(3): 389.
Moberg, P. J., Arnold, S. E., Doty, R. L., Gur, R. E., Balderston, C. C., Roalf, D. R., Gur, R. C., Kohler, C. G., Kanes, S. J., Siegel, S. J., and Turetsky, B. I., "Olfactory functioning in schizophrenia: relationship to clinical, neuropsychological, and volumetric MRI measures" Journal of clinical and experimental neuropsychology (2006) 28(8): 1444.
Maxwell, C. R., Liang, Y., Kelly, M. P., Kanes, S. J., Abel, T., and Siegel, S. J., "Mice expressing constitutively active Gsalpha exhibit stimulus encoding deficits similar to those observed in schizophrenia patients" Neuroscience (2006) 141(3): 1257.
Maxwell, C. R., Ehrlichman, R. S., Liang, Y., Trief, D., Kanes, S. J., Karp, J., and Siegel, S. J., "Ketamine produces lasting disruptions in encoding of sensory stimuli" The Journal of pharmacology and experimental therapeutics (2006) 316(1): 315.
Maxwell, C. R., Ehrlichman, R. S., Liang, Y., Gettes, D. R., Evans, D. L., Kanes, S. J., Abel, T., Karp, J., and Siegel, S. J., "Corticosterone modulates auditory gating in mouse" Neuropsychopharmacology (2006) 31(5): 897.
Irani, F., Platek, S. M., Panyavin, I. S., Calkins, M. E., Kohler, C., Siegel, S. J., Schachter, M., Gur, R. E., and Gur, R. C., "Self-face recognition and theory of mind in patients with schizophrenia and first-degree relatives" Schizophrenia research (2006) 88(1-3): 151.
Hahn, C. G., Wang, H. Y., Cho, D. S., Talbot, K., Gur, R. E., Berrettini, W. H., Bakshi, K., Kamins, J., Borgmann-Winter, K. E., Siegel, S. J., Gallop, R. J., and Arnold, S. E., "Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia" Nature medicine (2006) 12(7): 824.
Gur, R. E., Kohler, C. G., Ragland, J. D., Siegel, S. J., Lesko, K., Bilker, W. B., and Gur, R. C., "Flat affect in schizophrenia: relation to emotion processing and neurocognitive measures" Schizophrenia bulletin (2006) 32(2): 279.
Siegel, S. J., Maxwell, C. R., Majumdar, S., Trief, D. F., Lerman, C., Gur, R. E., Kanes, S. J., and Liang, Y., "Monoamine reuptake inhibition and nicotine receptor antagonism reduce amplitude and gating of auditory evoked potentials" Neuroscience (2005) 133(3): 729.
Ragland, J. D., Gur, R. C., Valdez, J. N., Loughead, J., Elliott, M., Kohler, C., Kanes, S., Siegel, S. J., Moelter, S. T., and Gur, R. E., "Levels-of-processing effect on frontotemporal function in schizophrenia during word encoding and recognition" The American journal of psychiatry (2005) 162(10): 1840.
Hans, M., Shimoni, K., Danino, D., Siegel, S. J., and Lowman, A., "Synthesis and characterization of mPEG-PLA prodrug micelles" Biomacromolecules (2005) 6(5): 2708.
Frankel, W. N., Beyer, B., Maxwell, C. R., Pretel, S., Letts, V. A., and Siegel, S. J., "Development of a new genetic model for absence epilepsy: spike-wave seizures in C3H/He and backcross mice" J Neurosci (2005) 25(13): 3452.
Davis, J. A., James, J. R., Siegel, S. J., and Gould, T. J., "Withdrawal from chronic nicotine administration impairs contextual fear conditioning in C57BL/6 mice" J Neurosci (2005) 25(38): 8708.
Budhian, A., Siegel, S. J., and Winey, K. I., "Production of haloperidol-loaded PLGA nanoparticles for extended controlled drug release of haloperidol" Journal of microencapsulation (2005) 22(7): 773.
Talbot, K., Eidem, W. L., Tinsley, C. L., Benson, M. A., Thompson, E. W., Smith, R. J., Hahn, C. G., Siegel, S. J., Trojanowski, J. Q., Gur, R. E., Blake, D. J., and Arnold, S. E., "Dysbindin-1 is reduced in intrinsic, glutamatergic terminals of the hippocampal formation in schizophrenia" The Journal of clinical investigation (2004) 113(9): 1353.
Maxwell, C. R., Liang, Y., Weightman, B. D., Kanes, S. J., Abel, T., Gur, R. E., Turetsky, B. I., Bilker, W. B., Lenox, R. H., and Siegel, S. J., "Effects of chronic olanzapine and haloperidol differ on the mouse N1 auditory evoked potential" Neuropsychopharmacology (2004) 29(4): 739.
Maxwell, C. R., Kanes, S. J., Abel, T., and Siegel, S. J., "Phosphodiesterase inhibitors: a novel mechanism for receptor-independent antipsychotic medications" Neuroscience (2004) 129(1): 101.
Irani, F., Dankert, M., and Siegel, S. J., "Patient and family attitudes toward schizophrenia treatment" Current psychiatry reports (2004) 6(4): 283.
Irani, F., Dankert, M., Brensinger, C., Bilker, W. B., Nair, S. R., Kohler, C. G., Kanes, S. J., Turetsky, B. I., Moberg, P. J., Ragland, J. D., Gur, R. C., Gur, R. E., and Siegel, S. J., "Patient attitudes towards surgically implantable, long-term delivery of psychiatric medicine" Neuropsychopharmacology (2004) 29(5): 960.
Gur, R. E., Kohler, C., Turetsky, B. I., Siegel, S. J., Kanes, S. J., Bilker, W. B., Brennan, A. R., and Gur, R. C., "A sexually dimorphic ratio of orbitofrontal to amygdala volume is altered in schizophrenia" Biological psychiatry (2004) 55(5): 512.
Gould, T. J., Bizily, S. P., Tokarczyk, J., Kelly, M. P., Siegel, S. J., Kanes, S. J., and Abel, T., "Sensorimotor gating deficits in transgenic mice expressing a constitutively active form of Gs alpha" Neuropsychopharmacology (2004) 29(3): 494.
Gelber, E. I., Kohler, C. G., Bilker, W. B., Gur, R. C., Brensinger, C., Siegel, S. J., and Gur, R. E., "Symptom and demographic profiles in first-episode schizophrenia" Schizophrenia research (2004) 67(2-3): 185.
Connolly, P. M., Maxwell, C., Liang, Y., Kahn, J. B., Kanes, S. J., Abel, T., Gur, R. E., Turetsky, B. I., and Siegel, S. J., "The effects of ketamine vary among inbred mouse strains and mimic schizophrenia for the P80, but not P20 or N40 auditory ERP components" Neurochemical research (2004) 29(6): 1179.
Siegel, S. J., Connolly, P., Liang, Y., Lenox, R. H., Gur, R. E., Bilker, W. B., Kanes, S. J., and Turetsky, B. I., "Effects of strain, novelty, and NMDA blockade on auditory-evoked potentials in mice" Neuropsychopharmacology (2003) 28(4): 675.
Ragland, J. D., Moelter, S. T., McGrath, C., Hill, S. K., Gur, R. E., Bilker, W. B., Siegel, S. J., and Gur, R. C., "Levels-of-processing effect on word recognition in schizophrenia" Biological psychiatry (2003) 54(11): 1154.
Kohler, C. G., Turner, T. H., Bilker, W. B., Brensinger, C. M., Siegel, S. J., Kanes, S. J., Gur, R. E., and Gur, R. C., "Facial emotion recognition in schizophrenia: intensity effects and error pattern" The American journal of psychiatry (2003) 160(10): 1768.
Gur, R. E., Kohler, C., Ragland, J. D., Siegel, S. J., Bilker, W. B., Loughead, J., Phend, N., and Gur, R. C., "Neurocognitive performance and clinical changes in olanzapine-treated patients with schizophrenia" Neuropsychopharmacology (2003) 28(11): 2029.
Connolly, P. M., Maxwell, C. R., Kanes, S. J., Abel, T., Liang, Y., Tokarczyk, J., Bilker, W. B., Turetsky, B. I., Gur, R. E., and Siegel, S. J., "Inhibition of auditory evoked potentials and prepulse inhibition of startle in DBA/2J and DBA/2Hsd inbred mouse substrains" Brain research (2003) 992(1): 85.
Bilker, W. B., Brensinger, C., Kurtz, M. M., Kohler, C., Gur, R. C., Siegel, S. J., and Gur, R. E., "Development of an abbreviated schizophrenia quality of life scale using a new method" Neuropsychopharmacology (2003) 28(4): 773.
Siegel, S. J., Winey, K. I., Gur, R. E., Lenox, R. H., Bilker, W. B., Ikeda, D., Gandhi, N., and Zhang, W. X., "Surgically implantable long-term antipsychotic delivery systems for the treatment of schizophrenia" Neuropsychopharmacology (2002) 26(6): 817.
Gur, R. C., Ragland, J. D., Moberg, P. J., Turner, T. H., Bilker, W. B., Kohler, C., Siegel, S. J., and Gur, R. E., "Computerized neurocognitive scanning: I. Methodology and validation in healthy people" Neuropsychopharmacology (2001) 25(5): 766.
Gur, R. C., Ragland, J. D., Moberg, P. J., Bilker, W. B., Kohler, C., Siegel, S. J., and Gur, R. E., "Computerized neurocognitive scanning: II. The profile of schizophrenia" Neuropsychopharmacology (2001) 25(5): 777.
Gazzaley, A. H., Siegel, S. J., Kordower, J. H., Mufson, E. J., and Morrison, J. H., "Circuit-specific alterations of N-methyl-D-aspartate receptor subunit 1 in the dentate gyrus of aged monkeys" Proceedings of the National Academy of Sciences of the United States of America (1996) 93(7): 3121.
Siegel, S. J., Janssen, W. G., Tullai, J. W., Rogers, S. W., Moran, T., Heinemann, S. F., and Morrison, J. H., "Distribution of the excitatory amino acid receptor subunits GluR2(4) in monkey hippocampus and colocalization with subunits GluR5-7 and NMDAR1" J Neurosci (1995) 15(4): 2707.
Siegel, S. J., Brose, N., Janssen, W. G., Gasic, G. P., Jahn, R., Heinemann, S. F., and Morrison, J. H., "Regional, cellular, and ultrastructural distribution of N-methyl-D-aspartate receptor subunit 1 in monkey hippocampus" Proceedings of the National Academy of Sciences of the United States of America (1994) 91(2): 564.
Siegel, S. J., Ginsberg, S. D., Hof, P. R., Foote, S. L., Young, W. G., Kraemer, G. W., McKinney, W. T., and Morrison, J. H., "Effects of social deprivation in prepubescent rhesus monkeys: immunohistochemical analysis of the neurofilament protein triplet in the hippocampal formation" Brain research (1993) 619(1-2): 299.
