Molecular Systems Biology Laboratory (PI: Ravi Radhakrishnan, PhD)
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Molecular systems biology through multiscale modeling and high-performance computing
| Our research interests lie at the interface of chemical physics and molecular biology. Our goal is to provide atomic and molecular level characterization of complex biomolecular systems and formulate quantitatively accurate microscopic models for predicting the interactions of various therapeutic agents with innate biochemical signaling mechanisms.
We employ several computational algorithms ranging from techniques to treat electronic structure, molecular dynamics, Monte Carlo simulations, stochastic kinetic equations, and complex systems analyses in conjunction with the theoretical formalisms of statistical and quantum mechanics, and high performance computing in massively parallel architectures.
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CURRENT RESEARCH
- DNA Repair & Molecular Carcinogenesis
- Receptor-mediated signaling in Cancer
- Multiscale Modeling of Targeted drug delivery
- Signal transduction in biochemical networks
| Positions Available
- Postdoctoral
- Graduate
- Undergraduate
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Principal Investigator: Ravi Radhakrishnan, PhD.
University of Pennsylvania School of Engineering and Applied Sciences
- Assistant Professor of Bioengineering
- Assistant Professor of Chemical & Biomolecular Engineering
- Cheminformatics Core of the Penn Center of Molecular Discovery
University of Pennsylvania School of Medicine
- Assistant Professor of Biochemistry and Biophysics
- Graduate Group Member Genomics & Computational Biology
- Member of Institute for Targeted Medicine and Therapeutics
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| Mailing Address
University of Pennsylvania
Department of Bioengineering
210 S. 33rd St., 240 Skirkanich Hall
Philadelphia, PA, 19104
Office: 540 Skirkanich Hall
Ph: 1 (215) 898 0487
Fax: 1(215) 573 2071
Email: rradhak@seas.upenn.edu
Lab: 540 Skirkanich Hall
Ph: 1( 215) 898 0592
| Education
- 1995 B. Tech., Indian Institute of Technology
- 2001 PhD, Cornell University
Postdoctoral Training:
- 2000-2002, Massachusetts Institute of Technology
- 2002-2004, New York University and the Courant Institute
- 2003, Howard Hughes Medical Institute
Honors:
- 1991-1995 CSIR Undergraduate Fellowship
- 1995-1996 Cornell University Graduate Fellowship
- 2003 Computational Associate of HHMI
- 2008 HP Young Investigator Award
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